Balance ONE probiotics do not need to be refrigerated. Thanks to our long-lasting probiotic strains and the patented BIO-tract delivery mechanism, your probiotics will still be going strong at expiration date. Just keep them in a cool, dry place.

They are made in the USA, in a GMP-certified, FDA-compliant facility. We use rigorous quality control to ensure the highest standards.

Have you ever bought a probiotic supplement and found that it had no effect? That’s probably because all of the probiotic strains were destroyed by your stomach acid. Balance ONE probiotics use a patented process to compress our probiotics into tablets. Research has shown that this process delivers 15 times as many bacteria through stomach acid and to the intestines.

Our probiotics are completely free of nuts, wheat, gluten, and dairy. They are vegan, completely non-GMO, and free from all preservatives and artificial colors or flavors. Our facilities are fully cGMP-compliant and operate to the highest standards. We use rigorous quality control to ensure that our supplements match what it says on the label.

Travelers diarrhea and digestive problems can be incredibly common while traveling. Changes in timezones, exposure to new bugs, and new foods can all contribute. Balance ONE probiotics are ideal to take while traveling because they are shelf-stable. And thanks to our innovative delivery system, they can be taken at any time of day, giving you one less thing to worry about.

The time of day, or whether you take it with or without food, is less important with our time-release probiotic. When the time-release tablets come into contact with moisture they form a gel coating that protects them from the acidic environment in your stomach. Tests have shown that they are 15 times more effective at surviving stomach acid, when compared to regular vegetable capsules. They also release their live bacteria over 8-10 hours instead of all at once.

One of the first and most obvious benefits that our customers see is usually in improved digestion. That often happens within the first few weeks. Changes like higher energy levels and stronger immunity come a little later, as the gut flora begin to rebalance and nutrient absorption improves. ​The exact timeframe depends on how imbalanced your gut was to start with, what your diet is, and many other factors!

The regular dose for our Probiotic is one tablet per day. That's what most of our customers do, but we also have customers who take a wide range of doses. Some take three or more per day, whereas others take only half a tablet per day. 

That's one major advantage of using the time-release tablets; if you have a sensitive gut, taking half a tablet is a good way to start taking the probiotic without causing any digestive upset.

There is a commonly-held misconception that it’s pointless to take probiotics alongside antibiotics, because the antibiotics will kill the good bacteria in the probiotic. This is very far from the truth.

There has been a tremendous amount of research into the use of probiotics to manage the side effects associated with antibiotics. Often these side effects are digestive symptoms like diarrhea, but there are also longer-term impacts like a weakening of immunity.

Probiotics have been consistently shown to reduce the side effects of antibiotics. They can prevent much of the damage to your gut flora and reduce the long-term impact on your gut health, digestion, and immunity.

There is one important thing to note. Remember to take your probiotic at least an hour apart from the antibiotic. That will prevent the good bacteria from being killed by the antibiotic.

Probiotic supplements are generally a much better option than fermented foods if you are histamine-intolerant.

Some strains of probiotic bacteria (e.g. L. bulgaricus) are histamine-producing. Other strains (e.g. L. acidophilus, L. paracasei, Lactococcus lactis) are histamine-neutral. Some strains (e.g. L. plantarum, B. infantis, B. longum, L. salivarius) are thought to have a histamine-lowering effect! The research is mixed on others - for example, some research studies have found L. casei and S. thermophilus to be histamine-producers, but others have shown them to be histamine-neutral!

Our probiotic wasn't specifically designed to be low-histamine, but it does contain mostly histamine-neutral and histamine-lowering strains. It contains two strains that may be histamine-producers or histamine-neutral, depending which research you read (L. casei and S. thermophilus). But it also contains proven histamine-degraders like L. plantarum, B. infantis, B. longum, and L. salivarius. The other strains are broadly histamine-neutral. It does not contain the biggest histamine-producers like L. bulgaricus.