Balance ONE SerraDefend

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SerraDefend contains a blend of systemic and digestive enzymes to fight biofilms, reduce inflammation, and promote good digestive health.

These enzymes include Serrapeptase, Nattokinase, Protease, Cellulase, Hemicellulase, Chitosanase, Amylase, Glucoamylase, and Beta-Glucanase.

Systemic enzymes like Serrapeptase and Nattokinase have the ability to break down biofilms. Pathogens like Candida albicans and Lyme use these biofilms to protect themselves from your immune system.

These systemic and digestive enzymes have also been shown to reduce inflammation and relieve minor joint pain.

Take 1 capsule per day. A bottle lasts for 60 days.


Take our biofilm-busting SerraDefend formula to rebalance your gut, reduce inflammation, and eliminate joint pain. SerraDefend contains a carefully-chosen blend of both systemic and digestive enzymes.

The systemic enzymes are Serrapeptase, which is often used for inflammation and joint pain, and Nattokinase, which is commonly used for healthy circulation. Both have been shown to inhibit biofilm formation.

The digestive enzymes in SerraDefend include Protease to break down proteins, Cellulase and Hemicellulase to break down cellulose, Chitosanase to break down chitosan, Amylase and Glucoamylase to break down carbohydrates, and Beta-Glucanase to break down beta-glucans.

All of these enzymes have been scientifically proven to support healthy digestion. Some of them have also been shown to inhibit biofilms, reduce inflammation, and relieve minor joint pain.


The natural ingredients in SerraDefend are:

Serrapeptase, Nattokinase, Protease, Cellulase, Hemicellulase, Chitosanase, Amylase, Glucoamylase, and Beta-Glucanase.

Other ingredients in this supplement are:

Cellulose (Vegan Capsule), Maltodextrin (as a carrier for the enzymes).


Dosage for SerraDefend:

Take one (1) capsule daily on an empty stomach, or as directed by a healthcare professional.

SerraDefend can be taken alongside any of our other supplements. It does not interact with probiotics or antifungal supplements.



SerraDefend is expertly formulated for biofilm defence, improved digestion, and lower inflammation.

The range of systemic and digestive enzymes in SerraDefend are known to have a range of benefits for overall health. Let's take a closer look.


SerraDefend contains 45,000 SPU of Serrapeptase, a proteolytic systemic enzyme commonly used for relief from mild joint pain and inflammation. Serrapeptase has also been shown to break down and dissolve biofilms, and can support healthy, balanced gut flora.


Nattokinase is a fibrinolytic systemic enzyme that promotes normal healing and repair in the human body. In the case of Nattokinase, it is most commonly used to promote healthy circulation. It can also assist your body in breaking down break down biofilms and supporting healthy digestion. Each dose of SerraDefend contains 700 FU of Nattokinase.


Proteases are a group of enzymes that help to break down proteins and promote healthy digestion. In the gut, they break down proteins into amino acids that are easily absorbed and play many critical roles in your body.


Cellulase is one of the only digestive enzymes that your body does not produce by itself. It is necessary to break down cellulose in cell walls, and it has also been shown to inhibit biofilm formation.


Hemicellulase is an enzyme that breaks down substances closely related to cellulase, like galactans, xylans, mannans, and arabans, which are also components of cell walls.


Chitosanase is an enzyme that breaks down chitosan, a key building block in the cell walls of yeast and many microorganisms. Chitosanase has the unique ability to break down these cell walls by helping your body to dissolve the chitosan.


Amylase is a digestive enzyme that assists your body in breaking down starches. It is naturally present in your saliva, promotes healthy digestion of carbohydrates, and has been shown to inhibit biofilm formation in a variety of microorganisms.


Glucoamylase is another digestive enzyme that helps us to break down starches, in this case the glucosidic linkages that hold the starches together. It can assist in healthy digestion and help to relieve digestive upset.


Beta-Glucanase is an enzyme that breaks down the glycosidic bonds within beta-glucans. These glucans form up to 60% of the cell walls and biofilms of many microorganisms, and beta-glucanase has in fact been shown to disrupt biofilm formation.


We stand behind our products, and your 100% satisfaction is our only goal.

If you don't absolutely love our SerraDefend formula, we'll be happy to issue a refund, no questions asked!
If you have any queries about our products, shipping, website, or any other questions at all, just get in touch using our contact form.
We aim to reply to all messages within 4 hours.

Customer Reviews

Based on 95 reviews
It Works!

These supplements in conjunction with the candida diet helped me get my candida under control. So grateful I was able to do that naturally without western meds. Thank you Balance One!


Love this product!

Dean (New Zealand)

Excellent product

Brock E. (United Kingdom)

the best enzyme product i have tried!


Love the way it helps with this Candida.


SerraDefend does not need to be refrigerated. However, it will stay freshest when stored in a cool, dry place.

SerraDefend is made in California, USA, using high-quality ingredients sourced from around the world, in a GMP-certified, FDA-compliant facility. We use rigorous quality control on our ingredients and processes to ensure the highest standards.

Almost all enzyme formulations use maltodextrin as the carrier for their enzymes, even though some of them choose not to include it on their Supplement Facts label. Our enzymes are a liquid and are sprayed on to maltodextrin to keep them stable. The amount of maltodextrin used is small.

SerraDefend is completely free of nuts, wheat, gluten, soy, and dairy. It is vegan, completely non-GMO, and free from all preservatives and artificial colors or flavors. Our facilities are fully cGMP-compliant and operate to the highest standards. In addition, we use rigorous quality control to ensure that our supplements match what it says on the label.

For some people, enzyme formulations like SerraDefend can cause mild digestive symptoms at first. They might include gas, bloating or mild diarrhea. These symptoms usually pass within a few days.

The capsules we use for SerraDefend are 0.72in long and 0.42in wide. They're quite compact and most of our customers find them very easy to swallow.

We recommend taking SerraDefend without food and at least one hour away from your meal. That will allow the systemic enzymes to pass through to your intestine safely. The exact time of day does not matter, but it should be at least an hour away from any meal.